ChemBK
  • Home
  • Product Category

4-Amino-2-Methyl-10H-Thieno[2,3-B]1,5Benzodiazepine HCl

4-Amino-2-Methyl-10H-Thiene[2,3,B][1,5]Benzodiazepine HCL

CAS: 138564-60-0

Molecular Formula: C12H12ClN3S

  1. Home
  2. Product Category
  3. pharmaceutical intermediates
  4. API intermediate
  5. 4-Amino-2-Methyl-10H-Thieno[2,3-B]1,5Benzodiazepine HCl

4-Amino-2-Methyl-10H-Thieno[2,3-B]1,5Benzodiazepine HCl - Names and Identifiers

Name 4-Amino-2-Methyl-10H-Thiene[2,3,B][1,5]Benzodiazepine HCL
Synonyms 3-b][1
OlanzaMine
5] benzodiazapine HCl
4-AMino-2-Methyl-10H-thieno[2
1H-1,2-benzodiazepine hydrochloride
4-Amino-2-Methyl-10H-[2,3-b][1,5]Benzodiazepine HCL
4-Amino-2-Methyl-10H-Thieno[2,3-B]1,5Benzodiazepine HCl
4-AMINO-2-METHYL-10H-THIONE[2,3-B][1,5]BENZODIAZEPINE HCL
4-Amino-2-Methyl-10H-Thieno[2,3-B][1,5]Benzodiazepine Hcl
4-Amino-2-Methyl-10H-Thiene[2,3,B][1,5]Benzodiazepine HCL
4-Amino-2-Methyl-10H-Thieno(2,3-B)(1,5) Benzodiazepine HCl
4-Amino-2-methyl-10H-thienol[2.3-B][1.5] Benzodiazepine HCl
4-Amino-2-Methyl-10H-Thieno-[2,3-b][1,5] Benzodiazepine HCl
4-Amino-2-Methyl-10H-Thieno [2,3-b] [1,5] Benzodiazepine HCl
2-Methyl-10H-thieno[2,3-b][1,5]benzodiazepin-4-aMine Hydrochloride
4-amino-2-methyl-10h-thiene[2,3-b][1,5]benzodiazepine hydrochloride
4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride
4-amino-2-methyl-10h-thieno(2,3,b)(1,5)benzodiazepine Hydrochloride
4-AMino-2-Methyl-10H-thienol[2.3-B][1.5]benzodiazepine hydrochloride
2-Methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-aMine hydrochloride
4-amino-2-methyl-10H-Thieno [2,3-b] [1,5] Benzodiazepine Hydrochloride
4-amino-2-methyl-10H-Thieno [2,3-b] [1,5] Benzodiazepine Hydrochloride(Intermediate for Olanzapine)
CAS 138564-60-0
EINECS 604-085-0
InChI InChI=1/C9H8N2.ClH/c1-2-6-9-8(4-1)5-3-7-10-11-9;/h1-7,11H;1H

4-Amino-2-Methyl-10H-Thieno[2,3-B]1,5Benzodiazepine HCl - Physico-chemical Properties

Molecular FormulaC12H12ClN3S
Molar Mass265.76
Melting Point283-285°C
Boling Point302.5°C at 760 mmHg
Flash Point136.7°C
Solubility DMSO (Slightly), Methanol (Sparingly, Sonicated)
Vapor Presure0.000739mmHg at 25°C
AppearanceYellow crystal solid
ColorYellow to Dark Beige
Storage ConditionKeep in dark place,Inert atmosphere,Store in freezer, under -20°C

4-Amino-2-Methyl-10H-Thieno[2,3-B]1,5Benzodiazepine HCl - Risk and Safety

Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

4-Amino-2-Methyl-10H-Thieno[2,3-B]1,5Benzodiazepine HCl - Reference Information

use 4-amino -2-methyl-10H-thiophene [2,3-b][1,5] benzodiazepine hydrochloride is yellow to dark beige solid at normal temperature and pressure, which is common in the synthesis of olanzapine tablets, a drug molecule for the treatment of schizophrenia.
synthesis method in a 500 ml round bottom flask equipped with a mechanical stirrer and thermometer, put 10.0g (0.0386 mol) 5-methyl -2-((2-nitrobenzene) amino) thiophene -3-nitrile (1) and 100 ml ethanol. Then 7.4g (0.062 mol) of tin powder and 84 ml of 4M hydrochloric acid were added, and the mixture was stirred at 50 ℃ for 0.5 hours. The temperature of the reaction mixture was raised to 85°C and the stirring was continued for 4 hours. The mixture was then cooled to 25°C and stirred for a further 8 hours, which resulted in the precipitation of solids. The precipitated crystals were collected, washed with 20mL of ethanol, and dried in a vacuum. 9.8g (96%)2 hydrochloride is a light yellow solid. mp. above 300 ° 8(HPLC>98.5%).
Last Update：2024-04-09 15:16:36
4-Amino-2-Methyl-10H-Thieno[2,3-B]1,5Benzodiazepine HCl
Supplier List
Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: 4-Amino-2-Methyl-10H-Thiene[2,3,B][1,5]Benzodiazepine HCL Request for quotation
CAS: 138564-60-0
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: 4-Amino-2-Methyl-10H-Thiene[2,3,B][1,5]Benzodiazepine HCL Request for quotation
CAS: 138564-60-0
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
Multiple SpecificationsSpot supply
Product Name: Olopatadine Impurity 44 Visit Supplier Webpage Request for quotation
CAS: 138564-60-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride Visit Supplier Webpage Request for quotation
CAS: 138564-60-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
Wuhan Boye Science And Technology Development Co., Ltd.
Product Name: 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride Request for quotation
CAS: 138564-60-0
Tel: 86-10-10086 81625225
Email: yeqim@boyechemicals.com
Mobile: 86-15387090420
QQ: 1377812380 Click to send a QQ message
Wechat: 15387090420
Shanghai Worldyang Chemical Co.,Ltd.
Product Name: 4-amino-2-methyl-10H-thieno-[2,3-b](1,5)benzodiazepine HCl Request for quotation
CAS: 138564-60-0
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228 Click to send a QQ message
Wechat: 13651600618
WhatsApp: +8613651600618
Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: 4-Amino-2-Methyl-10H-Thiene[2,3,B][1,5]Benzodiazepine HCL Request for quotation
CAS: 138564-60-0
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: 4-Amino-2-Methyl-10H-Thiene[2,3,B][1,5]Benzodiazepine HCL Request for quotation
CAS: 138564-60-0
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
Multiple SpecificationsSpot supply
Product Name: Olopatadine Impurity 44 Visit Supplier Webpage Request for quotation
CAS: 138564-60-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride Visit Supplier Webpage Request for quotation
CAS: 138564-60-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
Wuhan Boye Science And Technology Development Co., Ltd.
Product Name: 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride Request for quotation
CAS: 138564-60-0
Tel: 86-10-10086 81625225
Email: yeqim@boyechemicals.com
Mobile: 86-15387090420
QQ: 1377812380 Click to send a QQ message
Wechat: 15387090420
Shanghai Worldyang Chemical Co.,Ltd.
Product Name: 4-amino-2-methyl-10H-thieno-[2,3-b](1,5)benzodiazepine HCl Request for quotation
CAS: 138564-60-0
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228 Click to send a QQ message
Wechat: 13651600618
WhatsApp: +8613651600618
View History
4-Amino-2-Methyl-10H-Thieno[2,3-B]1,5Benzodiazepine HCl
  • Home
  • Product Category

© 2015, 2023 ChemBK.com All Rights Reserved | Build: 20230617001